Dimethyl Sulfoxide → 3,3-Diethoxypropiononitrile
反応式
[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5]Br)[CH3:2].[C-:10]#[N:11].[Na+].CS(C)=O>O>[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][C:10]#[N:11])[CH3:2]参加物
5
実験手順
A mixture of 8 g of bromo-acetaldehyde diethyl-acetal, 3 g of sodium-cyanide and 20 ml of dimethyl-sulfoxide is admixed at a temperature of 80° C. for 5 hours. The reaction mixture is poured on 80 ml of water, then twice extracted with 50 ml of chloroform. The chloroform extract is washed twice with 30 ml of water, dried on magnesium sulfate, then distilled in vacuo.
後処理
- extractiontwice extracted with 50 ml of chloroform
- extractionThe chloroform extract
- washis washed twice with 30 ml of water
- customdried on magnesium sulfate
- distillationdistilled in vacuo
出典と根拠
- ORDレコード
- ord-b84da5d5dbfa45d0a46ae7e2a8b4fbec
- 出典データセット
- uspto-grants-1992_05
- 特許番号
- US05116402
反応ノート
読み込み中…