化工社化工社 化学情報印刷レポート · 研究参考用
N-acetyl-L-methionine → 21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-acetyl-L-methionine | HCID 448580 | — |
| 反応物 | HCID 131717396 | HCID 131717396 | — |
| 生成物 | 21-[2-(Acetylamino)-4-methylthio-1-oxobutylthio]-9-fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | HCID 88494358 | 53.4% |
反応手順
The title compound (0.38 gm) was prepared from 9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione-21-thiol (0.50 gm) and N-acetyl-L-methionine (0.70 gm) in the same manner as in Synthetic Example 1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05116829 |
| 出典データセット | uspto-grants-1992_05 |
| ORD ID | ord-2f89926fca1d4e44a5c3e2e4e431581b |
| 出典メモ | uspto-grants-1992_05 |