化工社化工社 化学情報印刷レポート · 研究参考用
L-Cysteine, N-acetyl-S-ethyl- → 21-[2-(Acetylamino)-3-etylthio-1-oxopropylthio]-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | L-Cysteine, N-acetyl-S-ethyl- | HCID 147382 | — |
| 反応物 | 9-Fluoro-11,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-21-thiol | HCID 131717402 | — |
| 生成物 | 21-[2-(Acetylamino)-3-etylthio-1-oxopropylthio]-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione | HCID 88395374 | 29.5% |
反応手順
The title compound (0.21 gm) was prepared from 9-fluoro-11 ,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione-21-thiol (0.5 gm) and N-acetyl-S-ethylcysteine (0.70 gm) in the same manner as in Synthetic Example 1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05116829 |
| 出典データセット | uspto-grants-1992_05 |
| ORD ID | ord-8cb11f885d7e46b78341dadba13e2a42 |
| 出典メモ | uspto-grants-1992_05 |