Benzyl Chloride → Benzyldiphenylamine

HRID 1197239

反応式

HRID 1197239 の反応式
[CH2:1](OC1C=CC=CC=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:15]1([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(Cl)C1C=CC=CC=1>O>[C:22]1([N:21]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

参加物

5

反応物 3

HCID 7503Benzyl ChlorideHCID 11487DiphenylamineHCID 70352Benzyl Phenyl Ether

生成物 1

HCID 69080Benzyldiphenylamine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

N-phenylbanzaldimine (1.81 g, 0.010 mol) and benzylphenyl ether (1.84 g, 0.010 mol) were heated at 75° C. in Na/DMF solution (2.0 g; 50 mL) for 30 minutes. The solution was then poured in 200 mL of water, the precipitate was filtered washed with water and dried. Recrystallization from methanol, 70 mL, gave white needles (73% isolated) mp 88°-90° C. (lit mp 86°-7°C8, 88°-9°C9). No depression in melting point occurred when this material was admixed with an authentic sample prepared from diphenylamine and benzyl chloride.

後処理

  1. filtrationthe precipitate was filtered
  2. washwashed with water
  3. customdried
  4. customRecrystallization from methanol, 70 mL
  5. customgave white
  6. customneedles (73% isolated) mp 88°-90° C. (lit mp 86°-7°C8, 88°-9°C9)

出典と根拠

ORDレコード
ord-b56cadaf1ab140f5b653791f41ed18d3
出典データセット
uspto-grants-1992_05
特許番号
US05117062

関連ノート

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