化工社化工社 化学情報印刷レポート · 研究参考用
Pyridine → Gla-aht
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | 2,5-Methano-5H,9H-pyrimido(2,1-b)(1,5,3)dioxazepin-9-one, 2,3-dihydro-3-(hydroxymethyl)-8-methyl-, (2R,3R,5R)- | HCID 457982 | — |
| 生成物 | Gla-aht | HCID 6475485 | — |
反応手順
Anhydrothymidine (0.520 g, 2.319 mmol, as a dry white powder) was dissolved in anhydrous pyridine (10 ml) under an atmosphere of dry nitrogen, and to this stirred solution at room temperature was added GLA acid chloride (0.900 g, 3.02 mmol). Stirring was continued overnight after which period, TLC indicated complete loss of the starting material. The pyridine was
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05276020 |
| 出典データセット | uspto-grants-1994_01 |
| ORD ID | ord-f4b0413425a043e68a1a6429d3d68dea |
| 出典メモ | uspto-grants-1994_01 |