関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-Methyl-1-butanol | HCID 8723 | — |
| 反応物 | p-Dimethylsilylbenzoyl chloride | HCID 71434831 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2-Methylbutyl 4-dimethylsilylbenzoate | HCID 123524005 | — |
反応手順
20.0 g (0.101 mol) of 4-dimethylsilylbenzoyl chloride were added dropwise at 10° C.-15° C. to a solution of 8.90 g (0.101 mol) of 2-methylbutan-1-ol in 20 ml of dry pyridine. The reaction solution was stirred for one hour at 25° C., poured onto ice and acidified using HCl. The organic phase was separated off, diluted with toluene and washed by shaking three times with 10% HCl. It was washed with water and dried over sodium sulfate. After the toluene had been stripped off in vacuo on a rotary evaporator, distillation gave 2-methylbutyl 4-dimethylsilylbenzoate; boiling point 86° C.-110° C./0.05 mmHg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05277838 |
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| 出典データセット | uspto-grants-1994_01 |
|---|
| ORD ID | ord-6ffafd9ff23542d2a3db6da01bd2f2d4 |
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| 出典メモ | uspto-grants-1994_01 |
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