HCID 14775259、化合物 → HCID 178440008、化合物
反応式
[NH:1]([C:3]1[C:8]([CH2:9][CH2:10][CH3:11])=[N:7][C:6]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[CH:5][N:4]=1)[NH2:2].[NH:18]1[CH:22]=[C:21]([CH2:23][CH:24]([C:30](OCC)=O)[C:25]([O:27][CH2:28][CH3:29])=[O:26])[N:20]=[CH:19]1>>[NH:18]1[CH:22]=[C:21]([CH2:23][CH:24]([C:30]2[N:4]3[CH:5]=[C:6]([C:12]4[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=4)[N:7]=[C:8]([CH2:9][CH2:10][CH3:11])[C:3]3=[N:1][N:2]=2)[C:25]([O:27][CH2:28][CH3:29])=[O:26])[N:20]=[CH:19]1参加物
3
実験手順
In a manner analogous to that described in Example 1, by condensing 2-hydrazino-3-propyl-5-(3-pyridyl)pyrazine with diethyl (imidazol-4-yl-methyl)malonate (J.Chem.Soc. 99, (1911) 1390) there is obtained ethyl rac-α-(imidazol-4-ylmethyl)-8-propyl-6-(3-pyridyl)-s-triazolo[4,3-a]pyrazine-3-acetate, MS: 405 (M)+, which is converted into the above acid by saponification analogously to Example 1.
出典と根拠
- ORDレコード
- ord-967ffc8d1f74448d980e3a006ddceed5
- 出典データセット
- uspto-grants-1994_01
- 特許番号
- US05278161
反応ノート
読み込み中…