関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Chlorotrimethylsilane | HCID 6397 | — |
| 反応物 | 4-Chlorostyrene | HCID 14085 | — |
| 反応物 | Magnesium | HCID 5462224 | — |
| 反応物 | HCID 178436504 | HCID 178436504 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Trimethyl(4-vinylphenyl)silane | HCID 595282 | 45% |
反応手順
A solution of trimethylchlorosilane (7.82 g, 72.4 mmole) in dry tetrahydrofuran(THF) (40 mL) was added dropwise over a 90 minute period to a solution of (4-vinylphenyl)magnesium chloride, prepared from 4-vinylphenylchloride (10 g, 72.4 mmole) and magnesium (2.43 g, 100 mmole) in dry THF (100 mL). Temperature was maintained at 10° C. during the addition. The reaction mixture was stirred at room temperature over 20 hours under nitrogen atmosphere. The crude product was obtained by direct distillation at 45°-48° C./0.5 mm in 45% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05278244 |
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| 出典データセット | uspto-grants-1994_01 |
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| ORD ID | ord-57cb22bd90c44b30bf7df4e4f4f96655 |
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| 出典メモ | uspto-grants-1994_01 |
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