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Hydrazine hydrate (1:1) → 4-Phenoxybutan-1-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 2-(4-Phenoxybutyl)-1H-isoindole-1,3(2H)-dione | HCID 16637597 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-Phenoxybutan-1-amine | HCID 116240 | 96.2% |
反応手順
A mixture of N-(4-phenoxybutyl)phthalimide (7.8 g), hydrazine hydrate (7 ml) and ethanol (150 ml) was stirred for one hour under reflux. Crystalline precipitate was filtered off, then the filtrate was concentrated under reduced pressure to give 4-phenoxybutylamine (4.2 g, 95%) as an oily product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05280022 |
| 出典データセット | uspto-grants-1994_01 |
| ORD ID | ord-43de905befef4fd6a66a6a7f25f015a2 |
| 出典メモ | uspto-grants-1994_01 |