Ethyl Acetoacetate → Ethyl 2Z-[(4-hexylphenyl)methylene]-3-oxobutanoate

HRID 1198213

反応式

HRID 1198213 の反応式
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].[CH2:10]([C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>N1CCCCC1>[CH2:10]([C:16]1[CH:23]=[CH:22][C:19](/[CH:20]=[C:2](/[C:3](=[O:4])[CH3:5])\[C:1]([O:7][CH2:8][CH3:9])=[O:6])=[CH:18][CH:17]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

参加物

4

反応物 2

HCID 8868Ethyl AcetoacetateHCID 170813Benzaldehyde, 4-hexyl-

生成物 1

HCID 67820812Ethyl 2Z-[(4-hexylphenyl)methylene]-3-oxobutanoate

試薬・触媒・溶媒 1

HCID 8082Piperidine触媒

反応条件

温度
70 °C

実験手順

Ethyl acetoacetate (3.9g, 0.03 moles), parahexylbenzaldehyde (3.8g, 0.02 moles) and piperidine (3 drops) were stirred at room temperature for 20 hrs. and then stirred for 4 days at 70° C. Products A and B were separated and purified by silica gel chromatography. Structure assignments were supported by NMR, infrared and uv spectra and elemental analysis (302.4).

後処理

  1. customProducts A and B were separated
  2. custompurified by silica gel chromatography

出典と根拠

ORDレコード
ord-aa282224ed5b4f9c861e2e466cf56d88
出典データセット
uspto-grants-1994_01
特許番号
US05280047

関連ノート

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