Benzoylacetone → 2Z-[(4-hexylphenyl)methylene]-1-phenyl-1,3-butanedione

HRID 1198214

反応式

HRID 1198214 の反応式
[C:1]([CH2:9][C:10](=[O:12])[CH3:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:13]([C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][CH:20]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>N1CCCCC1.C(OCC)C>[CH2:13]([C:19]1[CH:26]=[CH:25][C:22](/[CH:23]=[C:9](/[C:10](=[O:12])[CH3:11])\[C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[O:8])=[CH:21][CH:20]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

参加物

5

反応物 2

HCID 7166Benzoylacetone2 回HCID 170813Benzaldehyde, 4-hexyl-

生成物 1

HCID 678204432Z-[(4-hexylphenyl)methylene]-1-phenyl-1,3-butanedione

試薬・触媒・溶媒 2

HCID 8082Piperidine触媒HCID 3283Diethyl Ether溶媒

実験手順

Benzoylacetone (0.65g, 0.004 moles), parahexylbenzaldehyde (0.76g, 0.004 moles) and piperidine (3 drops) were stirred in ethyl ether (10ml) for 20 hrs. An additional 200mg benzoylacetone was added and the solution stirred for 48 hrs. The solution was concentrated to an oil with a gentle stream of Nitrogen. The product was purified by silica gel chromatography. The structure assignment was supported by NMR, infrared and uv spectra and elemental analysis (334.5).

後処理

  1. concentrationThe solution was concentrated to an oil with a gentle stream of Nitrogen
  2. customThe product was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-534fa26faf7540c49b873a3ed7cde52c
出典データセット
uspto-grants-1994_01
特許番号
US05280047

関連ノート

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