Hexylamine → 2,2,2-Trifluoro-n-hexylacetamide

HRID 1199282ノート

反応式

[F:1][C:2]([F:9])([F:8])[C:3]([O:5]CC)=O.[CH2:10]([NH2:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>>[CH2:10]([NH:16][C:3](=[O:5])[C:2]([F:1])([F:8])[F:9])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

参加物

反応物 2

HCID 8102Hexylamine

HCID 9794Ethyl trifluoroacetate

生成物 1

HCID 5394242,2,2-Trifluoro-n-hexylacetamide

実験手順

In a manner similar to Example 6, ethyl trifluoroacetate (131 g, 0.92 m) was reacted with n-hexylamine. The resulting amide distilled at 64° C./0.2 mm Hg and amounted to 154 g.

後処理

distillationThe resulting amide distilled at 64° C./0.2 mm Hg

出典と根拠

ORDレコード: ord-3acd5797c63a4ed1a6f577ca9fca6167
出典データセット: uspto-grants-1990_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04899249

反応ノート

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