Acetic Acid → HCID 178527782、化合物

HRID 1199337

反応式

HRID 1199337 の反応式
CO[C:3]1[C:9](=O)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH2:11][C:12]([NH2:14])=[S:13].C[O-].[Na+].C(O)(=O)C>CO>[SH:13][C:12]1[N:11]=[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=[C:9]2[N:14]=1

参加物

6

反応物 4

HCID 176Acetic AcidHCID 165462-Methoxy-2,4,6-cycloheptatrien-1-oneHCID 2723790ThioureaHCID 10942334Sodium Methoxide

生成物 1

HCID 178527782HCID 178527782、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

According to the method disclosed in Journal of the American Chemical Society, vol. 76, pages 3352 and 3353 (1954), 150 g of 2-methoxytropone and 84 g of thiourea were added to 255 g of a solution of 28% sodium methoxide in methanol, and stirred at room temperature for 30 minutes. Further, 600 ml of methanol was added thereto and acetic acid was added until the pH of the solution becomes around 5. Deposited crystals were filtered and washed with methanol. The obtained crystals were added to 1 l of methanol, and refluxed with heating for 30 minutes. After being allowed to cool to room temperature, the crystals were filtered and dried.

後処理

  1. filtrationDeposited crystals were filtered
  2. washwashed with methanol
  3. additionThe obtained crystals were added to 1 l of methanol
  4. temperaturerefluxed
  5. temperaturewith heating for 30 minutes
  6. temperatureto cool to room temperature
  7. filtrationthe crystals were filtered
  8. customdried

出典と根拠

ORDレコード
ord-ea45f1326eab45b0a956340c01cdb20a
出典データセット
uspto-grants-1990_02
特許番号
US04900648

関連ノート

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