Thiophene-3-boronic acid → (4,4-Difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1-thiophen-3-yl-1H-indol-2-yl]-methanone

HRID 119999ノート

反応式

HRID 119999 の反応式
[F:1][C:2]1([F:29])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[nH:11][c:12]3[cH:13][cH:14][c:15]([O:19][CH:20]4[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]4)[cH:16][c:17]3[cH:18]2)[CH2:6][CH2:7]1.[s:30]1[cH:31][c:32]([B:35]([OH:36])[OH:37])[cH:33][cH:34]1>>[F:1][C:2]1([F:29])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[n:11](-[c:32]3[cH:31][s:30][cH:34][cH:33]3)[c:12]3[cH:13][cH:14][c:15]([O:19][CH:20]4[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]4)[cH:16][c:17]3[cH:18]2)[CH2:6][CH2:7]1

参加物

3

反応物 2

HCID 581760Thiophene-3-boronic acidHCID 11603838(4,4-Difluoropiperidin-1-yl)[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]methanone

生成物 1

HCID 16739595(4,4-Difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1-thiophen-3-yl-1H-indol-2-yl]-methanone

出典と根拠

ORDレコード
ord-90cb0b0bce4d425d82127f06134d3609
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反応ノート

読み込み中…