Potassium Hydroxide → HCID 19864515、化合物
反応式
C([O:4][CH2:5][CH2:6][CH2:7][CH2:8][N:9]1[C:17]2[CH:16]=[CH:15][N:14]=[CH:13][C:12]=2[N:11]=[C:10]1[CH3:18])(=O)C.[OH-].[K+]>C(O)C>[CH3:18][C:10]1[N:9]([CH2:8][CH2:7][CH2:6][CH2:5][OH:4])[C:17]2[CH:16]=[CH:15][N:14]=[CH:13][C:12]=2[N:11]=1参加物
4
実験手順
1-(4-Acetoxybutyl)-2-methylimidazo[4,5-c]pyridine (0.55 g) was dissolved in ethanol (10 ml) and 2M potassium hydroxide (2 ml) was added dropwise. The mixture was stirred at room temperature for 3 hours and then evaporated under vacuum. The residue was dissolved in 2M hydrochloric acid, washed with methylene chloride (2×20 ml), basified with solid NaHCO3 to pH 7.5 and then extracted with methylene chloride (10×20 ml). The combined organic extracts were evaporated under vacuum to leave the desired product as a brown oil (0.5 g).
後処理
- customevaporated under vacuum
- dissolutionThe residue was dissolved in 2M hydrochloric acid
- washwashed with methylene chloride (2×20 ml)
- extractionextracted with methylene chloride (10×20 ml)
- customThe combined organic extracts were evaporated under vacuum
出典と根拠
- ORDレコード
- ord-d4ab17044edb4fdf9b6ab1dfe37ddc4c
- 出典データセット
- uspto-grants-1990_02
- 特許番号
- US04904671
反応ノート
読み込み中…