4-Amino-1-butanol → HCID 19864525、化合物
反応式
[CH3:1][C:2]1O[C:4]([CH3:7])=[N:5][N:6]=1.[NH2:8][CH2:9][CH2:10][CH2:11][CH2:12][OH:13]>CN1CCCC1=O>[CH3:1][C:2]1[N:8]([CH2:9][CH2:10][CH2:11][CH2:12][OH:13])[C:4]([CH3:7])=[N:5][N:6]=1参加物
4
実験手順
2,5-Dimethyl-1,3,4-oxadiazole (3.8 g), 4-aminobutanol (3.5 g) and N-methylpyrrolidone (10 ml) were heated at 150° for 18 hours. The mixture was evaporated under high vacuum and the residue chromatographed on silica eluting with a mixture of ethyl acetate and methanol. The fractions containing the product were evaporated under vacuum to leave the title compound, (5.1 g), which was used directly.
後処理
- customThe mixture was evaporated under high vacuum
- customthe residue chromatographed on silica eluting with a mixture of ethyl acetate and methanol
- additionThe fractions containing the product
- customwere evaporated under vacuum
出典と根拠
- ORDレコード
- ord-2c839f4aff904142bcafac9adb3c4cd1
- 出典データセット
- uspto-grants-1990_02
- 特許番号
- US04904671
反応ノート
読み込み中…