化工社化工社 化学情報印刷レポート · 研究参考用
2-Cyclohexen-1-one, 4,4-dimethyl- → Cyclohexanone, 4,4-dimethyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Cyclohexen-1-one, 4,4-dimethyl- | HCID 136839 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | Cyclohexanone, 4,4-dimethyl- | HCID 138166 | 94% |
反応手順
A solution of 4,4-dimethyl-cyclohex-2-enone (3 mmol) in ethyl acetate is hydrogenated overnight at room temperature using Pd/C (0.05 mmol) with hydrogen under normal pressure. Filtration over celite and then concentration by evaporation produces 4,4-dimethyl-cyclohexanone (355 mg) in a yield of 94% (J. Org. Chem. 2001, 66 (3), 733-738).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07727979B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-4a9b7976539f4e5b878d784e3b817458 |
| 出典メモ | uspto-grants-2010_06 |