Hydrochloric Acid → N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]nicotinamide

反応式

[C:27]([c:28]1[cH:29][n:30][cH:31][cH:32][cH:33]1)(=[O:34])[Cl:35].[ClH:26].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH3:25])[c:6]([NH:7][c:8]2[n:9][c:10](-[c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[n:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[cH:24]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH3:25])[c:6]([NH:7][c:8]2[n:9][c:10](-[c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[n:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[cH:24]1)[C:27]([c:28]1[cH:29][n:30][cH:31][cH:32][cH:33]1)=[O:34]

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 82604Nicotinoyl chloride

HCID 227324584-(5-Amino-2-methylanilino)-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine

生成物 1

HCID 22732504N-[4-Methyl-3-(2-pyridin-4-yl-6-(trifluoromethyl)pyrimidin-4-ylamino)-phenyl]nicotinamide

出典と根拠

ORDレコード: ord-a6dead2cd15c4fa891fa2a83c3f31f2f
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…