Toluene → N-(2,5-Difluoro-4-(morpholinomethyl)phenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine

反応式

[Br:21][c:22]1[cH:23][c:24]([F:36])[c:25]([CH2:26][N:27]2[CH2:28][CH2:29][O:30][CH2:31][CH2:32]2)[cH:33][c:34]1[F:35].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[F:1][c:2]1[c:3](-[c:9]2[cH:10][n:11][c:12]([CH3:20])[n:13]2[CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:4][c:5]([NH2:8])[n:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:9]2[cH:10][n:11][c:12]([CH3:20])[n:13]2[CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:4][c:5]([NH:8][c:22]2[cH:23][c:24]([F:36])[c:25]([CH2:26][N:27]3[CH2:28][CH2:29][O:30][CH2:31][CH2:32]3)[cH:33][c:34]2[F:35])[n:6][cH:7]1