5-(3-Bromo-4-fluorophenyl)-3-(2,4-difluorophenyl)-[1,2,4]triazine → 3-(2,4-Difluorophenyl)-5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]-[1,2,4]triazine

反応式

[Br:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11](-[c:15]3[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:12][n:13][cH:14]2)[cH:5][cH:6][c:7]1[F:8].[F:23][c:24]1[c:25]([Sn:30]([CH2:31][CH2:32][CH2:33][CH3:34])([CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH2:41][CH3:42])[n:26][cH:27][cH:28][cH:29]1>>[c:2]1(-[c:25]2[c:24]([F:23])[cH:29][cH:28][cH:27][n:26]2)[cH:3][c:4](-[c:9]2[n:10][c:11](-[c:15]3[c:16]([F:22])[cH:17][c:18]([F:21])[cH:19][cH:20]3)[n:12][n:13][cH:14]2)[cH:5][cH:6][c:7]1[F:8]

参加物

反応物 2

HCID 103842555-(3-Bromo-4-fluorophenyl)-3-(2,4-difluorophenyl)-[1,2,4]triazine

HCID 164271503-Fluoro-2-(tributylstannyl)pyridine

生成物 1

HCID 117405943-(2,4-Difluorophenyl)-5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]-[1,2,4]triazine

出典と根拠

ORDレコード: ord-458555fe099a4ca4a2685866c02d3caf
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…