HCID 21025108、化合物 → 3-Cyano-4-[2-fluoro-4-(thiazol-2-yloxy)-phenylamino]-5-methyl-pyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester

反応式

[CH2:15]([CH3:16])[O:17][C:18](=[O:19])[c:20]1[c:21]([CH3:46])[c:22]2[n:23]([n:24][cH:25][c:26]([C:43]#[N:44])[c:27]2[NH:28][c:29]2[cH:30][cH:31][c:32]([S:33][c:34]3[n:35]([CH3:36])[cH:37][cH:38][n:39]3)[c:40]([Cl:41])[cH:42]2)[cH:45]1.[F:1][c:2]1[c:3]([NH2:14])[cH:4][cH:5][c:6]([O:8][c:9]2[s:10][cH:11][cH:12][n:13]2)[cH:7]1>>[F:1][c:2]1[c:3]([NH:14][c:27]2[c:22]3[c:21]([CH3:46])[c:20]([C:18]([O:17][CH2:15][CH3:16])=[O:19])[cH:45][n:23]3[n:24][cH:25][c:26]2[C:43]#[N:44])[cH:4][cH:5][c:6]([O:8][c:9]2[s:10][cH:11][cH:12][n:13]2)[cH:7]1

参加物

反応物 2

HCID 21025108HCID 21025108、化合物

HCID 221797212-Fluoro-4-(thiazol-2-yloxy)-phenylamine

生成物 1

HCID 210251123-Cyano-4-[2-fluoro-4-(thiazol-2-yloxy)-phenylamino]-5-methyl-pyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester

出典と根拠

ORDレコード: ord-a52436b2e10844a4b71b4c87e30ff29e
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…