1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → 5-Chloro-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1H-benzoimidazole

反応式

[Cl:1][c:2]1[nH:3][c:4]2[c:5]([n:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2.[F:16][C:17]([c:18]1[c:19]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:20][cH:21][cH:22][cH:23]1)([F:30])[F:31]>>[c:2]1([N:27]2[CH2:26][CH2:25][N:24]([c:19]3[c:18]([C:17]([F:16])([F:30])[F:31])[cH:23][cH:22][cH:21][n:20]3)[CH2:29][CH2:28]2)[n:3][c:4]2[c:5]([nH:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2

参加物

反応物 2

HCID 27777861-[3-(Trifluoromethyl)pyridin-2-yl]piperazine

HCID 1785060581H-Benzimidazole, 2,6-dichloro-5-(trifluoromethyl)-

生成物 1

HCID 578351415-Chloro-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1H-benzoimidazole

出典と根拠

ORDレコード: ord-ccbab8c42639497a830bb0408b2f876c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…