6-Chloro-3-(difluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine → 3-(Difluoromethyl)-6-[4-[1-(4-fluorophenyl)-1-methylethyl]piperazin-1-yl][1,2,4]triazolo[4,3-b]pyridazine

HRID 1212240

反応式

[Cl:17][c:18]1[cH:19][cH:20][c:21]2[n:22]([n:23]1)[c:24]([CH:27]([F:28])[F:29])[n:25][n:26]2.[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH3:9])([CH3:10])[N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH3:9])([CH3:10])[N:11]2[CH2:12][CH2:13][N:14]([c:18]3[cH:19][cH:20][c:21]4[n:22]([n:23]3)[c:24]([CH:27]([F:28])[F:29])[n:25][n:26]4)[CH2:15][CH2:16]2)[cH:6][cH:7]1