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2-Chloronicotinic acid → 2-chloro-N-[6-chloro-7-(4-methyl-piperazin-1-yl)-9H-beta-carbolin-8-yl]-nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloronicotinic acid | HCID 76258 | — |
| 反応物 | 6-chloro-7-(4-methyl-piperazin-1-yl)-8-amino-9H-beta-carboline | HCID 67166737 | — |
| 生成物 | 2-chloro-N-[6-chloro-7-(4-methyl-piperazin-1-yl)-9H-beta-carbolin-8-yl]-nicotinamide | HCID 11340022 | 25% |
反応手順
The desired compound was prepared according to Method A from 6-chloro-7-(4-methyl-piperazin-1-yl)-8-amino-9H-β-carboline and 2-chloro-nicotinic acid in 25% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07727985B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-e81169359fb94455a9946173265fc171 |
| 出典メモ | uspto-grants-2010_06 |