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HRID 12242作成日：2026年10月26日

2-(Methylamino)ethanol → (S)-4-{[(2-Hydroxy-ethyl)-methyl-carbamoyl]-methyl}-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amide

https://huagongshe.com/reaction/12242

反応式

関与物質

役割名称HCID仕込み量
反応物2-(Methylamino)ethanolHCID 8016—
反応物[(S)-5-(6-Chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholin-4-yl]-acetic acidHCID 11384512—
生成物(S)-4-{[(2-Hydroxy-ethyl)-methyl-carbamoyl]-methyl}-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-beta-carbolin-8-yl)-amideHCID 1150380055%

反応手順

The desired compound was prepared according to Method F from [(S)-5-(6-Chloro-9H-beta-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholin-4-yl]-acetic acid and 2-methylamino-ethanol in 55% yield.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07727985B2
出典データセットuspto-grants-2010_06
ORD IDord-fdc31d4a04884c65be3b0a14626b16d8
出典メモuspto-grants-2010_06