Bromobenzene → 2-(3-Bromo-phenyl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

反応式

[BH:26]([OH:27])[OH:28].[Br:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[CH3:1][c:2]1[cH:3][c:4](-[c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[cH:5][c:6]([O:8][S:9]([C:10]([F:11])([F:12])[F:13])(=[O:14])=[O:15])[n:7]1>>[CH3:1][c:2]1[cH:3][c:4](-[c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[cH:5][c:6](-[c:34]2[cH:33][cH:32][cH:31][c:30]([Br:29])[cH:35]2)[n:7]1

参加物

反応物 3

HCID 7961Bromobenzene

HCID 61668Boronic Acid

HCID 57468647Trifluoro-methanesulfonic acid 6-methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl ester

生成物 1

HCID 574687452-(3-Bromo-phenyl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine

出典と根拠

ORDレコード: ord-15802313e73b4e598489e4663363006e
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…