関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 4-Fluorophenethyl bromide | HCID 573153 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 4-Fluorophenethyltriphenylphosphonium bromide | HCID 22386745 | — |
反応手順
4-Fluorophenylethyl bromide (700 mg, 3.44 mmol) was dissolved in toluene (4 mL), triphenylphosphine (904 mg, 3.44 mmol) added and the solution heated for 10 min in a sealed flask at 200° C. under microwave heating. After cooling to rt, the solvent was decanted and the title compound was obtained quantitatively as the remaining glassy solid, which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07727999B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-ced818104f6646a0b4c67d321a5aa17e |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
