Acetyl chloride → Methyl 2-(2-iodophenyl)acetate

HRID 1242809

反応式

HRID 1242809 の反応式
[I:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[C:12](Cl)(=O)C>CO>[CH3:12][O:10][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[I:1]

参加物

4

反応物 2

HCID 6367Acetyl chlorideHCID 27800902-Iodophenylacetic acid

生成物 1

HCID 640185Methyl 2-(2-iodophenyl)acetate収率 100%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

2-Iodophenylacetic acid (1.45 g) was added to a mixture of methanol (100 mL) and acetyl chloride (5 mL). After stirring at room temperature for 3 hours, the solvent was removed and the residue was dried under vacuum giving the desired 2-iodophenylacetic acid methyl ester. Yield=100%

後処理

  1. customthe solvent was removed
  2. customthe residue was dried under vacuum

出典と根拠

ORDレコード
ord-9648dbe8a0734f798b9e731b9c3a0a62
出典データセット
uspto-grants-2006_10
特許番号
US07115741B2

関連ノート

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