関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Thiourea | HCID 2723790 | — |
| 反応物 | (E)-1-(4-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one | HCID 5375260 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178527862 | HCID 178527862 | — |
反応手順
To a solution of (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one (1.5 g, 7.2 mmol) in ethanol (25 ml) was added thiourea (0.60 g, 7.9 mmol) and potassium carbonate (K2CO3) (1.19 g. 8.63 mmol). The resulting suspension was heated to 85° C. for 12 hours then cooled to ambient temperature. The resulting solid was collected and thoroughly washed with water and hexanes to provide a beige solid: EI-MS (m/z) 222 [M+1]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07122544B2 |
|---|
| 出典データセット | uspto-grants-2006_10 |
|---|
| ORD ID | ord-7466dac3b45341168ec0e634a3e6fcb6 |
|---|
| 出典メモ | uspto-grants-2006_10 |
|---|
