Hydrochloric Acid → HCID 21919256、化合物
反応式
COC([C:5]1[N:6]=C[O:8][C:9]=1[CH2:10][C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)=O.[ClH:16]>>[ClH:16].[NH2:6][CH2:5][C:9](=[O:8])[CH2:10][C:11]1[S:12][CH:13]=[CH:14][CH:15]=1参加物
3
反応条件
- 温度
- 95 °C
実験手順
2.23 g 5-Thiophen-2-ylmethyl-oxazole-4-carboxylic acid methyl ester were suspended in 80 ml 6 N hydrochloric acid and stirred for 5 hours at 95° C. The solvent was removed at 30° C. under vacuum and the residue was suspended in ethylacetate, filtered and dried to yield 1.52 g (79%) 1-amino-3-thiophen-2-yl-propan-2-one hydrochloride; MS (ISP): m/e=156 (M+H+).
後処理
- customThe solvent was removed at 30° C. under vacuum
- filtrationfiltered
- customdried
出典と根拠
- ORDレコード
- ord-5366dae6e9404c1583c975c0174aa156
- 出典データセット
- uspto-grants-2006_10
- 特許番号
- US07122545B2
反応ノート
読み込み中…