2,4-Dichloro-6-methylbenzenesulfonyl chloride → N-(5-butyl-4-methyl-1,3-thiazol-2-yl)-2,4-dichloro-6-methylbenzenesulfonamide

HRID 1245640ノート

反応式

HRID 1245640 の反応式
[CH2:1]([C:5]1[S:9][C:8]([NH2:10])=[N:7][C:6]=1[CH3:11])[CH2:2][CH2:3][CH3:4].[Cl:12][C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([CH3:20])[C:14]=1[S:21](Cl)(=[O:23])=[O:22]>>[CH2:1]([C:5]1[S:9][C:8]([NH:10][S:21]([C:14]2[C:15]([CH3:20])=[CH:16][C:17]([Cl:19])=[CH:18][C:13]=2[Cl:12])(=[O:23])=[O:22])=[N:7][C:6]=1[CH3:11])[CH2:2][CH2:3][CH3:4]

参加物

3

反応物 2

HCID 28013872,4-Dichloro-6-methylbenzenesulfonyl chlorideHCID 21914683HCID 21914683、化合物

生成物 1

HCID 10200568N-(5-butyl-4-methyl-1,3-thiazol-2-yl)-2,4-dichloro-6-methylbenzenesulfonamide

実験手順

The title compound was prepared from 5-butyl-4-methyl-1,3-thiazol-2-ylamine (METHOD I) and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (41 mg) with purity >90%. MS (pos) m/z 393.2, 395.2.

出典と根拠

ORDレコード
ord-c8a6d497adbf467d8de04187023a9f81
出典データセット
uspto-grants-2006_10
特許番号
US07125900B2

反応ノート

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