Dimethylsulphamoyl chloride → N'-{2-[2-(4-Amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethoxy)ethyl}-N,N-dimethylsulfamide
反応式
[CH3:1][N:2]([CH3:7])[S:3](Cl)(=[O:5])=[O:4].[NH2:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][N:14]1[C:22]2[C:21]([CH3:23])=[C:20]([CH3:24])[N:19]=[C:18]([NH2:25])[C:17]=2[N:16]=[C:15]1[CH3:26]>>[NH2:25][C:18]1[C:17]2[N:16]=[C:15]([CH3:26])[N:14]([CH2:13][CH2:12][O:11][CH2:10][CH2:9][NH:8][S:3]([N:2]([CH3:7])[CH3:1])(=[O:5])=[O:4])[C:22]=2[C:21]([CH3:23])=[C:20]([CH3:24])[N:19]=1参加物
3
実験手順
Using the method of Examples 34–50, dimethylsulfamoyl chloride was reacted with 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The product was purified using Method A. The observed accurate mass was 371.1861.
出典と根拠
- ORDレコード
- ord-b50f4ca5d5e544a4afd945e98da0a45e
- 出典データセット
- uspto-grants-2006_10