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HRID 1247008作成日:2026年10月27日

Acetic Acid → Benzyl (S)-2-(7-amino-6-hydroxy-1H-indazol-1-yl)-1-methylethylcarbamate

https://huagongshe.com/reaction/1247008

反応式

関与物質

役割名称HCID仕込み量
反応物Acetic AcidHCID 176—
反応物Benzyl (S)-2-(6-hydroxy-7-nitro-1H-indazol-1-yl)-1-methylethylcarbamateHCID 136335131—
触媒IronHCID 23925—
溶媒WaterHCID 962—
生成物Benzyl (S)-2-(7-amino-6-hydroxy-1H-indazol-1-yl)-1-methylethylcarbamateHCID 136335132—

反応手順

The product from Step C (0.20 g, 0.54 mmol) was combined with acetic acid (5 mL), water (5 mL), and iron powder (0.30 g mmol) and stirred at room temperature for 1 h. The reaction mixture was filtered and evaporated to a dark oil (0.47 g) which was was used in the next reaction: LC/MS m/z 341.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07129257B1
出典データセットuspto-grants-2006_10
ORD IDord-d1ba1fe31dfe4f2d875d8394fc094a6c
出典メモuspto-grants-2006_10