2-(Tributylstannyl)-1,3-thiazole → 5-Methoxy-2-(4-methoxyphenyl)-7-(1,3-thiazol-2-yl)-1,3-benzoxazole
反応式
Br[C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19][CH3:20])[CH:3]=1.C([Sn](CCCC)(CCCC)[C:26]1[S:27][CH:28]=[CH:29][N:30]=1)CCC>>[CH3:20][O:19][C:4]1[CH:3]=[C:2]([C:26]2[S:27][CH:28]=[CH:29][N:30]=2)[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=1参加物
3
実験手順
The title compound was prepared according to the procedure of Example 53, Step a, from 7-bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole and 2-(tributylstannyl)thiazole. The product was obtained as an off white solid (93% yield, m.p. 132–136° C.); MS m/e 339 (M+H)+.
出典と根拠
- ORDレコード
- ord-f6a9a1ab0deb4808a793f6d19f63e6e5
- 出典データセット
- uspto-grants-2006_10
- 特許番号