化工社化工社 化学情報印刷レポート · 研究参考用
Iodoethane → tert-butyl N-ethyl-N-(prop-2-yn-1-yl)carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodoethane | HCID 6340 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | tert-butyl N-(prop-2-yn-1-yl)carbamate | HCID 11073648 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | tert-butyl N-ethyl-N-(prop-2-yn-1-yl)carbamate | HCID 18366151 | — |
反応手順
The sub-titled compound was prepared from tert-butyl prop-2-ynylcarbamate (0.6g), 60% sodium hydride (0.186 g), ethyl iodide (1.55 ml) and anhydrous N-methyl-2-pyrrolidinone (4 ml) by the method of Example 2(ii). The crude product was purified by chromatography on silica gel eluting with iso-hexane:ethyl acetate (19:1) to afford (0.34 g) of a colourless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07129246B2 |
| 出典データセット | uspto-grants-2006_10 |
| ORD ID | ord-5a3a9e4c2dc945ce9e5b489bb2fc660c |
| 出典メモ | uspto-grants-2006_10 |