化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Isoamyl Nitrite | HCID 8053 | — |
| 反応物 | 2-(5-amino-1H-pyrazol-1-yl)ethan-1-ol | HCID 320281 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso- | HCID 10149014 | 51.3% |
反応手順
To a solution of 5-amino-1-(2-hydroxyethyl)pyrazole (6.35 g) in a mixed solvent of ethanol (25 ml) and concentrated hydrochloric acid (0.035 ml) was added dropwise isoamyl nitrite (7.03 g). The mixture was stirred at room temperature for 17 hours. The crystalline residue was collected by filtration and dried in vacuo to give 5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole (4.0 g) as a solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07129232B2 |
| 出典データセット | uspto-grants-2006_10 |
| ORD ID | ord-caef93d0f1284e4084569b09d22d8d2d |
| 出典メモ | uspto-grants-2006_10 |