Acetic Acid → HCID 13476541、化合物
反応式
[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[CH:11][C:6]=1[C:7]([O:9]C)=O.C(O)(=O)C.[O-:19][C:20]#[N:21].[K+]>O>[OH:1][CH2:2][CH2:3][N:4]1[C:5]2[C:6](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:7](=[O:9])[NH:21][C:20]1=[O:19]参加物
5
実験手順
To a stirred mixture of 10 parts of methyl 2-[(2-hydroxyethyl)amino]benzoate and 100 parts of acetic acid is added dropwise a solution of 4.5 parts of potassium cyanate in 25 parts of water. Upon completion, stirring at room temperature is continued overnight. The reaction mixture is evaporated. The solid residue is stirred with water. The product is filtered off, washed with water and ethanol, and dried, yielding 5 parts (48%) of 1-(2-hydroxyethyl)-2,4(1H,3H)-quinazolinedione; mp. 273.6° C.
後処理
- customThe reaction mixture is evaporated
- stirringThe solid residue is stirred with water
- filtrationThe product is filtered off
- washwashed with water and ethanol
- customdried
出典と根拠
- ORDレコード
- ord-0c4b35458b164c9e885c697d6866d3e3
- 出典データセット
- uspto-grants-1985_06
- 特許番号
- US04522945
反応ノート
読み込み中…