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3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid → Methyl 4-hydroxy-3-methoxy-cinnamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid | HCID 709 | — |
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | Methyl 4-hydroxy-3-methoxy-cinnamate | HCID 16830 | — |
反応手順
The preparation was effected analogously to Example 1 from 25 g (0.129 mol) of 4-hydroxy-3-methoxy-cinnamic acid and 180 ml of methanol with concentrated sulphuric acid as the catalyst. For purification, it was chromatographed on silica gel with dichloromethane/diethyl ether (19:1). This gave 21.78 g of methyl 4-hydroxy-3-methoxy-cinnamate as a pale yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06335409B1 |
| 出典データセット | uspto-grants-2002_01 |
| ORD ID | ord-ecfe1b6085494f07b93e938c2ed914c2 |
| 出典メモ | uspto-grants-2002_01 |