Sodium Bicarbonate → HCID 178502623、化合物
反応式
[CH3:1][O:2][N:3]=[C:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[OH:15])[CH2:5][N+:6]([O-])=[O:7].C(=O)(O)[O-].[Na+]>O>[CH3:1][O:2][N:3]=[C:4]1[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][C:5]1=[N:6][OH:7]参加物
4
反応条件
- 温度
- 92.5 °C
実験手順
71.8 g of 1-(2-hydroxy-phenyl)-2-nitro-ethanone O-methyl-oxime are added to a solution of 121 g (0.342 mol) of sodium bicarbonate in 700 ml of water. Within 30 minutes, the mixture is heated to 90-95° C., on which undissolved starting material melts and reacts and the product crystallizes out. The mixture is cooled to 20° C. and the product is filtered off, washed with 500 ml of water a little at a time and air-dried. 57.4 g (91.3% of theory) of benzofuran-2,3-dione 3-(O-methyl-oxime) 2-oxime are obtained as a mixture of two stereoisomers.
後処理
- customreacts
- customthe product crystallizes out
- temperatureThe mixture is cooled to 20° C.
- filtrationthe product is filtered off
- washwashed with 500 ml of water a little at a time
- customair-dried
出典と根拠
- ORDレコード
- ord-2d79afc9a9714978b026552eeadcb0f4
- 出典データセット
- uspto-grants-2002_01
- 特許番号
- US06335454B1
反応ノート
読み込み中…