1-(4-Amino-2-methylquinolin-3-yl)ethanone → HCID 12019318、化合物

HRID 1250456ノート

反応式

HRID 1250456 の反応式
[Br:1][C:2]1[CH:23]=[CH:22][C:5]([CH2:6][NH:7][C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=[C:10]([CH3:18])[C:9]=2[C:19](=[O:21])[CH3:20])=[CH:4][CH:3]=1.NC1C2C(=CC=CC=2)N=C(C)C=1C(=O)C.BrC1C=CC(CBr)=CC=1[Cl:48]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][NH:7][C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=[C:10]([CH3:18])[C:9]=2[C:19](=[O:21])[CH3:20])=[CH:22][C:23]=1[Cl:48]

参加物

4

反応物 3

HCID 6722971-(4-Amino-2-methylquinolin-3-yl)ethanoneHCID 114628041-(4-(4-Bromobenzylamino)-2-methylquinolin-3-yl)ethanone2 回HCID 129473921-Bromo-4-(bromomethyl)-2-chlorobenzene

生成物 1

HCID 12019318HCID 12019318、化合物

実験手順

1-(4-(4-Bromo-3-chlorobenzylamino)-2-methylquinolin-3-yl)ethanone was synthesized by the same process as described for 1-(4-(4-bromobenzylamino)-2-methylquinolin-3-yl)ethanone (Example 1, Intermediate 2c) starting from 1-(4-amino-2-methylquinolin-3-yl)ethanone and 4-bromo-3-chlorobenzyl bromide. MS(ES+):403/405.

出典と根拠

ORDレコード
ord-b9ad399c344d4b478156e248ebd96c88
出典データセット
uspto-grants-2002_01
特許番号
US06339077B1

反応ノート

読み込み中…