Allylamine → 2-Allylamino-4-dodecylamino-6-nitroquinazoline

HRID 1250599

反応式

HRID 1250599 の反応式
Cl[C:2]1[N:11]=[C:10]([NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:25]([O-:27])=[O:26])[CH:8]=2)[N:3]=1.[CH2:28]([NH2:31])[CH:29]=[CH2:30]>O>[CH2:28]([NH:31][C:2]1[N:11]=[C:10]([NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:25]([O-:27])=[O:26])[CH:8]=2)[N:3]=1)[CH:29]=[CH2:30]

参加物

4

反応物 2

HCID 7853AllylamineHCID 183265162-Chloro-4-dodecylamino-6-nitroquinazoline

生成物 1

HCID 183265482-Allylamino-4-dodecylamino-6-nitroquinazoline収率 93.4%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 170 mg (0.44 mmol) of 2-chloro-4-dodecylamino-6-nitroquinazoline was added 1.70 ml (22.66 mmol) of allylamine, and then the resulting mixture was stirred at room temperature overnight. After water was added to the reaction solution, crystals thus precipitated were filtered to give 170 mg (93.4%) of the title compound.

後処理

  1. customthus precipitated
  2. filtrationwere filtered

出典と根拠

ORDレコード
ord-46e3260cc7e241ce9c3303d32471a74b
出典データセット
uspto-grants-2002_01
特許番号
US06339089B2

関連ノート

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