2-Bromothiophene → 2-(3-methylphenyl)thiophene
反応式
Br[C:2]1[S:3][CH:4]=[CH:5][CH:6]=1.[CH3:7][C:8]1[CH:9]=[C:10](B(O)O)[CH:11]=[CH:12][CH:13]=1>>[C:8]1([CH3:7])[CH:9]=[CH:10][CH:11]=[C:12]([C:2]2[S:3][CH:4]=[CH:5][CH:6]=2)[CH:13]=1参加物
3
実験手順
2-(3-tolyl)thiophene was prepared in the same manner as described in Example 117A using 2-bromothiophene and 3-methylphenylboronic acid. The crude product was purified by flash chromatography on silica gel using hexane as the eluent (86% yield).
後処理
- customThe crude product was purified by flash chromatography on silica gel
出典と根拠
- ORDレコード
- ord-3d9ae6eed0b24c8296139aec1c5ec55d
- 出典データセット
- uspto-grants-2002_01
- 特許番号
- US06342610B2
反応ノート
読み込み中…