反応式
[CH3:1][C:2]1[S:3][C:4](B(O)O)=[CH:5][CH:6]=1.Br[C:11]1[S:15][C:14]([S:16]([N:19]2[CH:23]=[CH:22][CH:21]=[CH:20]2)(=[O:18])=[O:17])=[CH:13][CH:12]=1>>[CH3:1][C:2]1[S:3][C:4]([C:11]2[S:15][C:14]([S:16]([N:19]3[CH:23]=[CH:22][CH:21]=[CH:20]3)(=[O:17])=[O:18])=[CH:13][CH:12]=2)=[CH:5][CH:6]=1参加物
3
実験手順
N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from 2-methylthiophene-5-boronic acid and N-(5-bromothiophene-2-sulfonyl)pyrrole. Purification by column chromatography using 2% ether/hexanes gave the pure sulfonamide in 72% yield as a white solid.
後処理
- customPurification by column chromatography
出典と根拠
- ORDレコード
- ord-dd6866d1bdf74d7ca4f8a73c4b1fb383
- 出典データセット
- uspto-grants-2002_01
- 特許番号
- US06342610B2
関連ノート
読み込み中…