Hydroxide → 4-[2-(Imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acid

HRID 1251905ノート

反応式

HRID 1251905 の反応式
[N:1]1([CH2:6][CH:7]([C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][CH:27]=2)[O:8][C:9]2[CH:18]=[CH:17][C:12]([C:13]([O:15]C)=[O:14])=[C:11]([C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH:10]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[OH-]>CO>[N:1]1([CH2:6][CH:7]([C:26]2[CH:27]=[CH:28][C:29]([F:32])=[CH:30][CH:31]=2)[O:8][C:9]2[CH:18]=[CH:17][C:12]([C:13]([OH:15])=[O:14])=[C:11]([C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH:10]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

参加物

4

反応物 2

HCID 961HydroxideHCID 18324444Methyl 4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl)benzoate

生成物 1

HCID 539166304-[2-(Imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acid

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl) benzoic acid was prepared from methyl 4-[2-(imidazol-1-yl)-1-(4-fluorophenyl)ethoxy]-2-(4-fluorophenyl)benzoate by treatment with aqueous hydroxide in methanol and used without further purification.

後処理

  1. customused without further purification

出典と根拠

ORDレコード
ord-7dea7ac90af34a5797c93fe450543583
出典データセット
uspto-grants-2002_01
特許番号
US06342765B1

反応ノート

読み込み中…