Cetyl Alcohol → HCID 13392722、化合物

HRID 1252170ノート

反応式

HRID 1252170 の反応式
[C:1]([O:4][CH:5]1[O:10][CH:9]([CH:11]([CH3:13])[CH3:12])[C:8](=[O:14])[CH:7]=[CH:6]1)(=O)[CH3:2].[CH2:15](O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]CC>C(OCC)C>[CH2:1]([O:4][CH:5]1[O:10][CH:9]([CH:11]([CH3:13])[CH3:12])[C:8](=[O:14])[CH:7]=[CH:6]1)[CH2:2][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH3:15]

参加物

4

反応物 2

HCID 2682Cetyl AlcoholHCID 159178365-Oxo-6-(propan-2-yl)-5,6-dihydro-2H-pyran-2-yl acetate

生成物 1

HCID 13392722HCID 13392722、化合物収率 92.1%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

In 50 ml of ethyl ether were dissolved 3.96 g of 6-acetoxy-2-isopropyl-2H-pyran-3(6H)-one and 4.84 g of cetyl alcohol with stirring. Into the solution was gradually added 0.1 ml of anhydrous stannic chloride at a temperature of 5° to 10° C. The reaction mixture was stirred at room temperature for 7 hours, washed twice with aqueous sodium hydrogencarbonate solution and once with saturated aqueous sodium chloride solution and then dried over anhydrous magnesium sulfate. By the distillation of solvent was obtained 7.0 g of 6-cetyloxy-2-isopropyl-2H-pyran-3(6H)-one [compound 1] in a yellow viscous oily form.

後処理

  1. customat a temperature of 5° to 10° C
  2. stirringThe reaction mixture was stirred at room temperature for 7 hours
  3. washwashed twice with aqueous sodium hydrogencarbonate solution and once with saturated aqueous sodium chloride solution
  4. dry with materialdried over anhydrous magnesium sulfate
  5. distillationBy the distillation of solvent

出典と根拠

ORDレコード
ord-2bbdbd9c8d5b49af95d8b17b6e9b6476
出典データセット
uspto-grants-1988_05
特許番号
US04742078

反応ノート

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