Ammonia → N-ethyl-4-amino-2-oxo-3-pentenesulfonamide

HRID 1252246ノート

反応式

HRID 1252246 の反応式
[CH2:1]([N:3]1[C:8]([CH3:9])=[CH:7][C:6](=[O:10])[CH2:5][S:4]1(=[O:12])=[O:11])[CH3:2].[NH3:13]>CO>[CH2:1]([NH:3][S:4]([CH2:5][C:6](=[O:10])[CH:7]=[C:8]([NH2:13])[CH3:9])(=[O:12])=[O:11])[CH3:2]

参加物

4

反応物 2

HCID 222AmmoniaHCID 201410202-ethyl-3-methyl-1,2-thiazin-5(6H)-one 1,1-dioxide

生成物 1

HCID 86742149N-ethyl-4-amino-2-oxo-3-pentenesulfonamide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A suspension of 13 g of 2-ethyl-3-methyl-1,2-thiazin-5(6H)-one 1,1-dioxide in 130 ml of methanol was reacted with ammonia in accordance with the procedure described in Example 1. The dark yellow solution obtained was concentrated to dryness under reduced pressure and the crystalline residue was recrystallized from ethanol. There were obtained 12.2 g of N-ethyl-4-amino-2-oxo-3-pentenesulfonamide in the form of colorless crystals, m.p. 112°-114°.

後処理

  1. customThe dark yellow solution obtained
  2. concentrationwas concentrated to dryness under reduced pressure
  3. customthe crystalline residue was recrystallized from ethanol

出典と根拠

ORDレコード
ord-24c2ec5fe40a4c70968c5a5bad14646d
出典データセット
uspto-grants-1988_05
特許番号
US04742069

反応ノート

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