Potassium Hydroxide → HCID 13799028、化合物
反応式
[C:1]([CH:3]1[C:6]2=[CH:7][C:8]([O:11][CH3:12])=[CH:9][CH:10]=[C:5]2[CH2:4]1)#[N:2].[OH-].[K+]>C(O)C.O.CCOCC>[NH2:2][CH2:1][CH2:3][CH2:12][O:11][C:8]1[CH:7]=[C:6]2[CH:3]([CH2:1][N:2]3[CH2:7][CH2:6][CH2:5][CH2:10][CH2:9]3)[CH2:4][C:5]2=[CH:10][CH:9]=1参加物
6
実験手順
1-Cyano-5-methoxybenzocyclobutene (29 g) is stirred with saturated KOH in ethanol (180 ml) for about 12 hours under nitrogen at RT. Water (60 ml) is added to the reaction mixture which is refluxed for about 3 hours. The mixture is cooled to RT, diluted with water, washed with ether and the aqueous layer acidified forming an oil. The oil is dissolved in ether and the ethereal solution washed, dried over Na2SO4, filtered and evaporated in vacuo affording the desired product as an oil.
後処理
- temperatureis refluxed for about 3 hours
- washwashed with ether
- customthe aqueous layer acidified forming an oil
- washthe ethereal solution washed
- dry with materialdried over Na2SO4
- filtrationfiltered
- customevaporated in vacuo
出典と根拠
- ORDレコード
- ord-80a025fb0e61435d805432b6c04cd60e
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04743600
反応ノート
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