Butyrate → HCID 53726930、化合物
反応式
O[CH:2]([C:12]1[CH:17]=[CH:16][C:15]([S:18][CH3:19])=[CH:14][CH:13]=1)[CH:3]([NH:6][C:7]([O:9]CC)=[O:8])CO.[K].C([O-])(=[O:25])CCC>C1(C)C=CC=CC=1>[CH3:19][S:18][C:15]1[CH:14]=[CH:13][C:12]([CH:2]2[O:9][C:7](=[O:8])[NH:6][CH:3]2[OH:25])=[CH:17][CH:16]=1参加物
5
実験手順
Compound (F) (5 g; 17.5 mmols) has been dissolved in warm toluene (25 ml). To this solution, an equimolar amount of potassium ter.butyrate has been added and the reaction mixture has been refluxed for 3 hours. Afterwards, almost all the solvent has been evaporated; water and ice have been added to the residue and the precipitate has been collected by filtration. The thus obtained crude (G) has been recrystallized from ethanol (3.7 g; yield, 88%); m.p. 130°-131° C.
後処理
- temperaturethe reaction mixture has been refluxed for 3 hours
- customAfterwards, almost all the solvent has been evaporated
- additionwater and ice have been added to the residue
- filtrationthe precipitate has been collected by filtration
出典と根拠
- ORDレコード
- ord-10217b9c5658465e95e4bba6a385c6fb
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04743700
反応ノート
読み込み中…