反応式
OS(O)(=O)=O.O[C:7]1[CH2:12][CH2:11][CH2:10][C:9](=[O:13])[C:8]=1[CH2:14][C:15](=[O:17])[CH3:16]>C(Cl)Cl>[CH3:16][C:15]1[O:17][C:7]2[CH2:12][CH2:11][CH2:10][C:9](=[O:13])[C:8]=2[CH:14]=1参加物
4
実験手順
To a solution of conc. H2SO4 (300 ml) cooled in an ice-bath was added a solution of 3-hydroxy-2(2-oxopropyl)-2-cyclohexene-1-one (190 g in 300 ml CH2Cl2). Upon completion of addition, the mixture was stirred at ambient temperature for about 1 hour. The mixture was then slowly poured into 3 l ice water, and then about 1 l of CH2Cl2 was added. The layers are separated and the aqueous layer extracted thrice with CH2Cl2 and the combined CH2Cl2 layers again extracted thrice with water. The CH2Cl2 layer washed thrice with dilute aqueous NaHCO3, then once with water and dried (MgSO4). Concentration in vacuo afford an orange oil.
後処理
- additionUpon completion of addition
- customThe layers are separated
- extractionthe aqueous layer extracted thrice with CH2Cl2
- washThe CH2Cl2 layer washed thrice with dilute aqueous NaHCO3
- dry with materialonce with water and dried (MgSO4)
- concentrationConcentration in vacuo
- customafford an orange oil
出典と根拠
- ORDレコード
- ord-27938cde0583418c82206b978208bd88
- 出典データセット
- uspto-grants-1988_05
- 特許番号
- US04745222
関連ノート
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