2-(Trifluoromethyl)acrylic acid → 3-Acetylthio-2-trifluoromethylpropanoic acid

HRID 1252806

反応式

HRID 1252806 の反応式
[C:1]([OH:6])(=[S:5])[CH:2](C)O.[F:7][C:8]([F:15])([F:14])[C:9](=[CH2:13])[C:10]([OH:12])=[O:11]>>[C:1]([S:5][CH2:13][CH:9]([C:8]([F:15])([F:14])[F:7])[C:10]([OH:12])=[O:11])(=[O:6])[CH3:2]

参加物

3

反応物 2

HCID 5876942-(Trifluoromethyl)acrylic acidHCID 178473673HCID 178473673、化合物

生成物 1

HCID 128330143-Acetylthio-2-trifluoromethylpropanoic acid

実験手順

A mixture of thiolactic acid (50 g) and 2-(trifluoromethyl)acrylic acid [M. W. Buxton, et al., J. Chem Soc., 366 (1954)] (66 g) is heated on the steam bath for one hour and then stored at room temperature for eighteen hours. The reaction mixture is distilled in vacuo to give 3-acetylthio-2-trifluoromethylpropanoic acid.

後処理

  1. temperatureis heated on the steam bath for one hour
  2. waitstored at room temperature for eighteen hours
  3. distillationThe reaction mixture is distilled in vacuo

出典と根拠

ORDレコード
ord-460d5ee2dd4142559165013c581f2b6b
出典データセット
uspto-grants-1988_05
特許番号
US04745124

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